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CS-W001157 4
Total: USD 88.00

BPBA

  • CAS No. 223463-14-7

  • Cat. No. CS-W015531
  • Purity≥98%
  • MDL No.MFCD03411558

*For research and further manufacturing use only, not for direct human use.

BPBA|CS-W015531

Structure of 223463-14-7

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General Information

  • CAS No. 223463-14-7
  • Cat. No. CS-W015531
  • Purity ≥98%
  • MDL No. MFCD03411558
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₅BBrNO₂
  • Molecular Weight 201.82
  • Synonym(s) 2-Bromopyridine-5-boronic acid
  • SMILES OB(C1=CC=C(Br)N=C1)O

Application

BPBA serves as a versatile building block in synthetic organic chemistry, enabling efficient construction of functionalized aromatic systems. Its robust stability and compatibility with standard coupling reactions facilitate reliable incorporation into complex molecular architectures. The molecule functions effectively in palladium-catalyzed cross-coupling protocols and serves as a key intermediate in the synthesis of heterocyclic scaffolds and bioactive compounds.

Synthesis

  • Route1
    • In-stock
      2,5-Dibromopyridine|CS-W001991
      624-28-2
    • null|null
      5419-55-6
    • ~71%
    • In-stock
      BPBA|CS-W015531
      223463-14-7

    References

    • RIB-X PHARMACEUTICALS, INC.; DUFFY, Erin, M. Patent: WO2012/125832 A2, 2012 ; Location in patent: Page/Page column 80 ; WO 2012/125832 A2
  • Route2

    References

    • Burzicki, Gregory; Voisin-Chiret, Anne Sophie; Oliveira Santos, Jana Sopkova-de; Rault, Sylvain Tetrahedron, 2009 , vol. 65, # 27 p. 5413 - 5417
  • Route3

    References

    • Bouillon, Alexandre; Lancelot, Jean-Charles; Collot, Valerie; Bovy, Philippe R; Rault, Sylvain Tetrahedron, 2002 , vol. 58, # 14 p. 2885 - 2890

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   53.35
  • LogP   -0.4761
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   1

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