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CS-W001157 4
Total: USD 88.00

(S)-AntPhos

  • CAS No. 1807740-34-6

  • Cat. No. CS-0020504
  • Purity≥97%
  • MDL No.MFCD31630706

*For research and further manufacturing use only, not for direct human use.

(S)-AntPhos|CS-0020504

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General Information

  • CAS No. 1807740-34-6
  • Cat. No. CS-0020504
  • Purity ≥97%
  • MDL No. MFCD31630706
  • Storage 4°C, protect from light, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₅H₂₃OP
  • Molecular Weight 370.42
  • Synonym(s) (3S)-4-(9-Anthracenyl)-3-(1,1-dimethylethyl)-2,3-dihydro-1,3-benzoxaphosphole; 1,3-Benzoxaphosphole, 4-(9-anthracenyl)-3-(1,1-dimethylethyl)-2,3-dihydro-, (3S)-
  • SMILES CC(C)(C)[P@]1C2=C(C3=C(C=CC=C4)C4=CC5=C3C=CC=C5)C=CC=C2OC1

Application

(S)-AntPhos serves as a highly effective chiral ligand in palladium-catalyzed cross-coupling reactions, enabling enantioselective C–C and C–heteroatom bond formation. Its robust steric and electronic profile enhances reaction efficiency and stereoselectivity across diverse substrates, including aryl halides and triflates. The ligand exhibits excellent bench stability, simplifies purification, and is compatible with standard synthetic workflows, making it a practical choice for asymmetric synthesis in medicinal chemistry and process development.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

Quality Control

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Computational Chemistry Data

  • TPSA   9.23
  • LogP   6.9156
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   1

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