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Structure of 1803416-27-4
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This chiral oxazole features a (S)-configured stereocenter and integrates a trifluoromethyl-substituted pyridine ring, enhancing electron deficiency and metabolic stability. The fused dihydrooxazole core provides rigidity and facilitates incorporation into complex heterocyclic scaffolds. Designed for medicinal chemistry applications, this building block enables efficient access to bioactive molecules through palladium-catalyzed cross-coupling and functionalization reactions under standard conditions.
(S)-4-Methyl-2-(5-(trifluoromethyl)pyridin-2-yl)-4,5-dihydrooxazole serves as a versatile chiral building block in medicinal chemistry, enabling access to diverse heterocyclic scaffolds. Its pyridine-trifluoromethyl moiety enhances metabolic stability and modulates electronic properties, while the dihydrooxazole ring provides a reactive handle for selective transformations. Bench-stable and compatible with standard synthetic protocols, it facilitates efficient synthesis of complex targets through functional group interconversions and coupling reactions.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: