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(1S,3R)-Methyl 3-aminocyclopentanecarboxylate hydrochloride

  • CAS No. 180323-49-3

  • Cat. No. CS-0042523
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(1S,3R)-Methyl 3-aminocyclopentanecarboxylate hydrochloride|CS-0042523

Structure of 180323-49-3

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General Information

  • CAS No. 180323-49-3
  • Cat. No. CS-0042523
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₄ClNO₂
  • Molecular Weight 179.64
  • Synonym(s) Methyl (1S,3R)-3-aminocyclopentane-1-carboxylate hydrochloride
  • SMILES O=C([C@@H]1C[C@H](N)CC1)OC.[H]Cl

Description

This chiral building block features a stereochemically defined (1S,3R) core with a methyl ester and protonated amine, enabling direct incorporation into bioactive scaffolds. The hydrochloride salt enhances solubility and stability under standard handling conditions, facilitating use in peptide synthesis and medicinal chemistry campaigns.

Application

(1S,3R)-Methyl 3-aminocyclopentanecarboxylate hydrochloride serves as a stereochemically defined building block for bioactive molecule synthesis, enabling efficient access to cyclopentane-based scaffolds prevalent in medicinal chemistry. The amine functionality offers direct derivatization potential via amidation or alkylation, while the carboxylate ester supports orthogonal transformations. Bench-stable and readily purified, it facilitates scalable synthesis of chiral intermediates with high diastereoselectivity.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   52.32
  • LogP   0.7086
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

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