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Methyl (1R,3S)-3-aminocyclopentane-1-carboxylate hydrochloride

  • CAS No. 180196-56-9

  • Cat. No. CS-0049307
  • Molecule weight179.64
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Methyl (1R,3S)-3-aminocyclopentane-1-carboxylate hydrochloride|CS-0049307

Structure of 180196-56-9

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General Information

  • CAS No. 180196-56-9
  • Cat. No. CS-0049307
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₄ClNO₂
  • Molecular Weight 179.64
  • Synonym(s) Cis(1R,2S)-Methyl 3-aMinocyclopentanecarboxylate hydrochloride
  • SMILES Cl.COC(=O)[C@@H]1CC[C@H](N)C1

Description

Methyl (1R,3S)-3-aminocyclopentane-1-carboxylate hydrochloride is a stereochemically defined cyclopentane derivative featuring a primary amine and ester functional group in a rigid, chiral scaffold. This bench-stable, moisture-tolerant salt facilitates direct incorporation into peptide mimetics and bioactive molecule synthesis under standard conditions.

Application

Methyl (1R,3S)-3-aminocyclopentane-1-carboxylate hydrochloride serves as a stereochemically defined building block for cyclopentane-based scaffolds in medicinal chemistry. The protected amine and ester functionalities enable sequential transformations, including peptide coupling, reductive amination, and cyclization reactions. Bench-stable and readily purified by standard techniques, it facilitates efficient access to bioactive heterocycles and conformationally restricted analogs relevant to GPCR-targeted drug discovery.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   52.32
  • LogP   0.7086
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

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