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CS-W001157 4
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Methyl (1R,3S)-3-aminocyclopentane-1-carboxylate hydrochloride

  • CAS No. 180196-56-9

  • Cat. No. CS-0049307
  • Purity≥97%
  • MDL No.None
  • HazMat Fee +

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    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Methyl (1R,3S)-3-aminocyclopentane-1-carboxylate hydrochloride|CS-0049307

Structure of 180196-56-9

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Description

Methyl (1R,3S)-3-aminocyclopentane-1-carboxylate hydrochloride is a stereochemically defined cyclopentane derivative featuring a primary amine and ester functional group in a rigid, chiral scaffold. This bench-stable, moisture-tolerant salt facilitates direct incorporation into peptide mimetics and bioactive molecule synthesis under standard conditions.

Application

Methyl (1R,3S)-3-aminocyclopentane-1-carboxylate hydrochloride serves as a stereochemically defined building block for cyclopentane-based scaffolds in medicinal chemistry. The protected amine and ester functionalities enable sequential transformations, including peptide coupling, reductive amination, and cyclization reactions. Bench-stable and readily purified by standard techniques, it facilitates efficient access to bioactive heterocycles and conformationally restricted analogs relevant to GPCR-targeted drug discovery.

General Information

  • CAS No. 180196-56-9
  • Cat. No. CS-0049307
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₄ClNO₂
  • Molecular Weight 179.64
  • Synonym(s) Cis(1R,2S)-Methyl 3-aMinocyclopentanecarboxylate hydrochloride
  • SMILES Cl.COC(=O)[C@@H]1CC[C@H](N)C1

Computational Chemistry Data

  • TPSA   52.32
  • LogP   0.7086
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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