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CS-W001157 4
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5-Iodo-1H-indazole

  • CAS No. 55919-82-9

  • Cat. No. CS-D1249
  • Purity≥97%
  • MDL No.MFCD07781642

*For research and further manufacturing use only, not for direct human use.

5-Iodo-1H-indazole|CS-D1249

Structure of 55919-82-9

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General Information

  • CAS No. 55919-82-9
  • Cat. No. CS-D1249
  • Purity ≥97%
  • MDL No. MFCD07781642
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₅IN₂
  • Molecular Weight 244.03
  • Synonym(s) 1H-indazole, 5-iodo-
  • SMILES IC1=CC2=C(NN=C2)C=C1

Description

5-Iodo-1H-indazole is a bench-stable heterocyclic building block featuring a iodinated indazole core. This electron-deficient scaffold integrates readily into C–H functionalization and cross-coupling reactions, enabling efficient access to bioactive molecules in medicinal chemistry and materials science applications.

Application

5-Iodo-1H-indazole serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions such as Suzuki, Stille, and Negishi couplings. The iodine substituent provides high reactivity under standard conditions, facilitating efficient C–C bond formation with arylboranes, stannanes, and zinc reagents. Its stability under ambient conditions and compatibility with diverse functional groups make it ideal for constructing complex heterocyclic scaffolds in API development.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   28.68
  • LogP   2.1675
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   0

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