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Methyl (S)-2-(morpholin-3-yl)acetate hydrochloride

  • CAS No. 1799443-47-2

  • Cat. No. CS-0097095
  • Purity≥98%
  • MDL No.MFCD28401047

*For research and further manufacturing use only, not for direct human use.

Methyl (S)-2-(morpholin-3-yl)acetate hydrochloride|CS-0097095

Structure of 1799443-47-2

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General Information

  • CAS No. 1799443-47-2
  • Cat. No. CS-0097095
  • Purity ≥98%
  • MDL No. MFCD28401047
  • Storage Store at room temperature, keep dry and cool
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₄ClNO₃
  • Molecular Weight 195.64
  • Synonym(s) (S)-Methyl 2-(morpholin-3-yl)acetate hydrochloride
  • SMILES O=C(OC)C[C@@H]1NCCOC1.[H]Cl

Description

Methyl (S)-2-(morpholin-3-yl)acetate hydrochloride features a chiral morpholinyl-acetate scaffold with enhanced solubility and stability under standard conditions. The hydrochloride salt form improves handling and crystallinity, while the (S)-configuration ensures stereochemical purity for asymmetric synthesis applications. This compound integrates readily into peptide couplings and serves as a key intermediate in medicinal chemistry workflows.

Application

Methyl (S)-2-(morpholin-3-yl)acetate hydrochloride serves as a chiral building block for medicinal chemistry, enabling the efficient construction of bioactive heterocycles and peptidomimetics. The morpholin-3-yl moiety provides enhanced solubility and metabolic stability, while the ester functionality allows for selective derivatization. Its bench-stable hydrochloride salt form facilitates handling and purification in standard synthetic workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H332-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   47.56
  • LogP   -0.0403
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   2

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