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Structure of 179811-81-5
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Methyl 2-amino-2-(3-(trifluoromethyl)phenyl)acetate hydrochloride features a benzylic amine scaffold flanked by a trifluoromethyl group and a methyl ester, delivering enhanced solubility and stability under standard conditions. This bench-stable salt form facilitates direct use in synthetic sequences requiring nitrogen incorporation or transition-metal-catalyzed coupling reactions.
Methyl 2-amino-2-(3-(trifluoromethyl)phenyl)acetate hydrochloride serves as a versatile building block for heterocyclic synthesis, enabling efficient access to substituted indoles and benzimidazoles via standard cyclization protocols. The trifluoromethyl group enhances metabolic stability and lipophilicity, while the amino and ester functionalities offer orthogonal reactivity for downstream modifications. Bench-stable and readily purified by crystallization, it functions reliably in multi-step sequences common to medicinal chemistry and process development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P280-P302+P352
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Lot numbers can be found on the outside label of a product: