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Structure of 17880-57-8
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5-Ethynylpicolinic acid features a terminal alkyne group conjugated to a pyridine ring, enabling efficient copper-catalyzed azide-alkyne cycloaddition (CuAAC) for bioconjugation and materials assembly. This bench-stable, moisture-tolerant reagent integrates readily into diverse molecular architectures via click chemistry protocols under standard conditions.
5-Ethynylpicolinic acid serves as a versatile building block in synthetic organic chemistry, enabling efficient access to functionalized heterocycles via copper-catalyzed azide-alkyne cycloaddition (CuAAC). Its ortho-carboxylic acid and terminal alkyne groups offer orthogonal reactivity, facilitating modular conjugation and scaffold diversification. The compound exhibits good bench stability and is amenable to standard purification techniques, making it well-suited for applications in medicinal chemistry and materials science.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: