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CS-W001157 4
Total: USD 88.00

trans-4-(Aminomethyl)cyclohexanemethanol

  • CAS No. 17879-23-1

  • Cat. No. CS-0069300
  • Purity≥95%
  • MDL No.MFCD14702919

*For research and further manufacturing use only, not for direct human use.

trans-4-(Aminomethyl)cyclohexanemethanol|CS-0069300

Structure of 17879-23-1

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General Information

  • CAS No. 17879-23-1
  • Cat. No. CS-0069300
  • Purity ≥95%
  • MDL No. MFCD14702919
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₇NO
  • Molecular Weight 143.23
  • Synonym(s) None
  • SMILES C(N)[C@H]1CC[C@H](CO)CC1

Description

trans-4-(Aminomethyl)cyclohexanemethanol features a rigid cyclohexane scaffold with equatorial amine and hydroxyl groups, enabling precise stereochemical control in medicinal chemistry. This bench-stable, moisture-tolerant building block integrates readily into bioactive scaffolds, particularly for CNS-targeted therapeutics and kinase inhibitors.

Application

trans-4-(Aminomethyl)cyclohexanemethanol serves as a versatile bifunctional building block in medicinal chemistry, enabling the construction of constrained bioactive scaffolds. Its stable trans-cyclohexane framework provides defined stereochemistry, while the pendant primary amine and hydroxymethyl groups offer orthogonal reactivity for conjugation, derivatization, or protection strategies. The compound exhibits excellent bench stability and compatibility with standard peptide coupling and reductive amination protocols, facilitating efficient synthesis of target molecules in drug discovery campaigns.

Safety Information

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GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 3259
Class : 8
Packing Group : Ⅲ
Hazard Statements : H314-H318
Precautionary Statements : P260-P264-P280-P304+P340-P330-P363-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   46.25
  • LogP   0.7438
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   2

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