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CS-W001157 4
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Methyl trans-4-(aminomethyl)cyclohexane-1-carboxylate hydrochloride

  • CAS No. 29275-88-5

  • Cat. No. CS-0048875
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Methyl trans-4-(aminomethyl)cyclohexane-1-carboxylate hydrochloride|CS-0048875

Structure of 29275-88-5

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General Information

  • CAS No. 29275-88-5
  • Cat. No. CS-0048875
  • Purity ≥97%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₈ClNO₂
  • Molecular Weight 207.70
  • Synonym(s) trans-4-(Aminomethyl)cyclohexanecarboxylic Acid Methyl Ester Hydrochloride
  • SMILES Cl.COC(=O)[C@H]1CC[C@H](CN)CC1

Description

Methyl trans-4-(aminomethyl)cyclohexane-1-carboxylate hydrochloride features a rigid, conformationally constrained cyclohexane scaffold with a pendant aminomethyl group and ester functionality. This bench-stable salt delivers a protected amine for late-stage diversification in medicinal chemistry campaigns.

Application

Methyl trans-4-(aminomethyl)cyclohexane-1-carboxylate hydrochloride serves as a versatile chiral building block for medicinal chemistry and peptide mimetics. The trans-configured cyclohexane ring provides defined stereochemistry, while the pendant aminomethyl group enables straightforward functionalization via alkylation, acylation, or reductive amination. The hydrochloride salt enhances solubility and stability, facilitating handling and purification in standard synthetic workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   52.32
  • LogP   1.3463
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   2

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