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CS-W001157 4
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4-(Bromomethyl)-2-methoxypyridine hydrobromide

  • CAS No. 2288708-87-0

  • Cat. No. CS-0514065
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

4-(Bromomethyl)-2-methoxypyridine hydrobromide|CS-0514065

Structure of 2288708-87-0

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General Information

  • CAS No. 2288708-87-0
  • Cat. No. CS-0514065
  • Purity ≥95%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₉Br₂NO
  • Molecular Weight 282.96
  • Synonym(s) None
  • SMILES BrCC1=CC(OC)=NC=C1.Br

Description

4-(Bromomethyl)-2-methoxypyridine hydrobromide features a reactive bromomethyl group flanked by an electron-rich pyridine ring and a methoxy substituent, enabling efficient coupling in nucleophilic substitution reactions. This bench-stable, moisture-tolerant reagent integrates seamlessly into synthetic workflows requiring selective alkylation under mild conditions.

Application

4-(Bromomethyl)-2-methoxypyridine hydrobromide serves as a versatile electrophilic building block for C–H functionalization and nucleophilic substitution reactions. The bromomethyl group enables efficient coupling with amines, thiols, and carbon nucleophiles under mild conditions, while the pyridine ring provides enhanced solubility and stability in polar solvents. Its bench-stable nature and compatibility with diverse functional groups make it well-suited for constructing complex heterocyclic scaffolds in medicinal chemistry and process development workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS05,GHS07
Signal Word : Danger
UN#: 3261
Class : 8
Packing Group : Ⅱ
Hazard Statements : H302-H314-H335
Precautionary Statements : P260-P264-P270-P271-P280-P301+P330+P331-P304+P340-P363-P405-P501

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Computational Chemistry Data

  • TPSA   22.12
  • LogP   2.563
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   2

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