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CS-W001157 4
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7-Bromo-3-methyl-3H-imidazo[4,5-c]pyridine

  • CAS No. 1784125-40-1

  • Cat. No. CS-0146047
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

7-Bromo-3-methyl-3H-imidazo[4,5-c]pyridine|CS-0146047

Structure of 1784125-40-1

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General Information

  • CAS No. 1784125-40-1
  • Cat. No. CS-0146047
  • Purity ≥97%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₆BrN₃
  • Molecular Weight 212.05
  • Synonym(s) 7-bromo-3-methylimidazo[4,5-c]pyridine
  • SMILES CN1C=NC2=C1C=NC=C2Br

Description

7-Bromo-3-methyl-3H-imidazo[4,5-c]pyridine is a heterocyclic scaffold featuring a brominated imidazopyridine core with a methyl substituent at the 3-position. This electron-deficient system enables efficient coupling in cross-coupling reactions and serves as a key building block in medicinal chemistry for targeted kinase inhibitors and bioactive small molecules.

Application

7-Bromo-3-methyl-3H-imidazo[4,5-c]pyridine serves as a versatile heterocyclic building block for medicinal chemistry and catalytic synthesis. Its bromine at C7 enables palladium-catalyzed cross-coupling reactions, while the methyl group at C3 offers site-specific functionalization. The imidazopyridine core provides structural rigidity and favorable pharmacophore characteristics, enhancing its utility in constructing complex scaffolds for drug discovery and materials science applications.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   30.71
  • LogP   1.7308
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   0

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