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Structure of 17809-36-8
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2-Fluoro-6-nitroaniline features a fluorine atom at the ortho position and a nitro group at the para position relative to the amino functionality, creating a strongly electron-deficient aromatic system. This combination enhances reactivity in electrophilic substitution processes and supports efficient coupling reactions. The compound exhibits bench-stable handling characteristics and integrates readily into complex molecular architectures.
2-Fluoro-6-nitroaniline serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling direct functionalization at the aniline nitrogen and ortho-fluorine positions. Its electron-deficient aromatic ring facilitates nucleophilic substitution, while the nitro group supports subsequent reductions and coupling reactions. The compound exhibits good bench stability and is compatible with standard purification protocols, making it well-suited for multi-step syntheses involving Suzuki-Miyaura, Buchwald-Hartwig, or amide bond formation.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: