Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

(4-(Difluoromethoxy)phenyl)methanamine

  • CAS No. 177842-14-7

  • Cat. No. CS-0107252
  • Purity≥95%
  • MDL No.MFCD00236231

*For research and further manufacturing use only, not for direct human use.

(4-(Difluoromethoxy)phenyl)methanamine|CS-0107252

Structure of 177842-14-7

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 177842-14-7
  • Cat. No. CS-0107252
  • Purity ≥95%
  • MDL No. MFCD00236231
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₉F₂NO
  • Molecular Weight None
  • Synonym(s) 4-(Difluoromethoxy)benzylamine
  • SMILES NCC1=CC=C(OC(F)F)C=C1

Description

This difluoromethoxy-substituted aniline derivative features a benzene ring bearing a para-difluoromethoxy group and a primary amine at the benzylic position. The electron-withdrawing nature of the difluoromethoxy moiety enhances amine basicity while improving metabolic stability, making this compound valuable for medicinal chemistry applications requiring enhanced membrane permeability and resistance to oxidative degradation.

Application

(4-(Difluoromethoxy)phenyl)methanamine serves as a versatile building block in medicinal chemistry, enabling the synthesis of bioactive compounds through standard amine functionalization. Its difluoromethoxy substituent enhances metabolic stability and modulates lipophilicity, while the primary amine facilitates conjugation reactions, reductive amination, and peptide coupling. The compound exhibits good bench stability and is readily purified by chromatography or crystallization, supporting scalable synthesis and integration into diverse heterocyclic scaffolds.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 2735
Class : 8
Packing Group : Ⅲ
Hazard Statements : H314-H318
Precautionary Statements : P280-P301+P330+P331-P302+P352-P304+P340

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   35.25
  • LogP   1.7467
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   3

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • (4-(Difluoromethoxy)phenyl)methanamine sigma(4-(Difluoromethoxy)phenyl)methanamine manufacturer(4-(Difluoromethoxy)phenyl)methanamine price(4-(Difluoromethoxy)phenyl)methanamine structure(4-(Difluoromethoxy)phenyl)methanamine SDSbuy (4-(Difluoromethoxy)phenyl)methanamine(4-(Difluoromethoxy)phenyl)methanamine supplier(4-(Difluoromethoxy)phenyl)methanamine uses(4-(Difluoromethoxy)phenyl)methanamine molecular weightprice of (4-(Difluoromethoxy)phenyl)methanamine(4-(Difluoromethoxy)phenyl)methanamine chemical name formula of (4-(Difluoromethoxy)phenyl)methanamine
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label