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Structure of 176548-70-2
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3-Bromo-5-fluorobenzoic acid features a benzene ring bearing bromine at the meta position relative to the carboxylic acid and fluorine at the para position, delivering enhanced electronic modulation and metabolic stability. This dual-heteroatom substitution enables precise tuning of reactivity in cross-coupling processes and facilitates incorporation into bioactive scaffolds requiring halogen-directed functionalization.
3-Bromo-5-fluorobenzoic acid serves as a valuable building block for pharmaceutical and agrochemical synthesis, enabling direct functionalization at the ortho position relative to the carboxylic acid. Its bromine and fluorine substituents offer orthogonal reactivity for palladium-catalyzed cross-coupling and nucleophilic aromatic substitution, respectively. The compound exhibits good bench stability and facilitates efficient purification via recrystallization, making it well-suited for scalable synthesis workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P260-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: