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Structure of 1244642-73-6
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3-Bromo-4,5-difluorobenzoic acid features a strategically positioned bromine and two fluorine substituents on the aromatic ring, enabling selective functionalization in cross-coupling reactions. This electron-deficient scaffold integrates readily into pharmaceutical intermediates and agrochemical building blocks, offering enhanced metabolic stability and tunable solubility under standard conditions.
3-Bromo-4,5-difluorobenzoic acid serves as a versatile building block in medicinal chemistry and materials science, enabling direct incorporation of bromo- and difluoro-substituted aromatic cores. The carboxylic acid group facilitates amidation, esterification, and coupling reactions, while the ortho-bromo functionality supports palladium-catalyzed cross-couplings. Bench-stable and readily purified by recrystallization, it functions as a key intermediate in the synthesis of fluorinated heterocycles and bioactive scaffolds.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: