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Structure of 212631-85-1
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5-Bromo-2,3,4-trifluorobenzoic acid features a trifluorinated aromatic core with strategic bromine and carboxylic acid placement, enabling direct functionalization in cross-coupling reactions. This electron-deficient scaffold integrates efficiently into bioactive molecule synthesis, offering enhanced metabolic stability and favorable solubility under standard conditions.
5-Bromo-2,3,4-trifluorobenzoic acid serves as a versatile building block for the synthesis of fluorinated heterocycles and pharmaceutical intermediates. Its orthogonal reactivity enables efficient Suzuki-Miyaura and Buchwald-Hartwig couplings, while the carboxylic acid group facilitates direct derivatization or activation. Bench-stable and readily purified by recrystallization, it functions reliably in multi-step synthetic sequences requiring high functional group tolerance.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P405-P501
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Lot numbers can be found on the outside label of a product: