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Structure of 175965-83-0
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2-Fluoro-4-methoxypyridine is a bench-stable heterocyclic building block featuring a fluorine atom at the 2-position and a methoxy group at the 4-position. This electron-deficient pyridine scaffold enables efficient coupling reactions, particularly in palladium-catalyzed cross-couplings, where the ortho-fluorine facilitates selective functionalization. Its moisture-tolerant nature simplifies handling under standard laboratory conditions.
2-Fluoro-4-methoxypyridine serves as a versatile building block in medicinal chemistry, enabling efficient late-stage functionalization via palladium-catalyzed cross-coupling reactions. Its ortho-fluoro substituent facilitates nucleophilic substitution under mild conditions, while the para-methoxy group enhances solubility and modulates electronic properties. The compound exhibits excellent bench stability and compatibility with diverse reaction conditions, making it ideal for constructing heterocyclic scaffolds and API intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: