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CS-W001157 4
Total: USD 88.00

1-Boc-4-(2-Formylphenyl)piperazine

  • CAS No. 174855-57-3

  • Cat. No. CS-W013995
  • Purity≥98%
  • MDL No.MFCD05864664

*For research and further manufacturing use only, not for direct human use.

1-Boc-4-(2-Formylphenyl)piperazine|CS-W013995

Structure of 174855-57-3

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General Information

  • CAS No. 174855-57-3
  • Cat. No. CS-W013995
  • Purity ≥98%
  • MDL No. MFCD05864664
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₆H₂₂N₂O₃
  • Molecular Weight 290.36
  • Synonym(s) TERT-BUTYL 4-(2-FORMYLPHENYL)PIPERAZINE-1-CARBOXYLATE
  • SMILES C2=C(N1CCN(C(OC(C)(C)C)=O)CC1)C(=CC=C2)C=O

Synthesis

  • Route1
    • In-stock
      2-Fluorobenzaldehyde|CS-W008891
      446-52-6
    • N-Boc-piperazine Olaparib Impurity|CS-0214004
      57260-71-6
    • ~91%
    • In-stock
      1-Boc-4-(2-Formylphenyl)piperazine|CS-W013995
      174855-57-3

    References

    • Dyck, Brian; Parker, Jessica; Phillips, Teresa; Carter, Lee; Murphy, Brian; Summers, Robin; Hermann, Julia; Baker, Tracy; Cismowski, Mary; Saunders, John; Goodfellow, Val Bioorganic and Medicinal Chemistry Letters, 2003 , vol. 13, # 21 p. 3793 - 3796
  • Route2

    References

    • Journal of Medicinal Chemistry, , vol. 47, # 3 p. 744 - 755
  • Route3
    • In-stock
      Di-tert-butyl dicarbonate|CS-0017817
      24424-99-5
    • 2-Piperazin-1-yl-benzaldehyde|CS-0213352
      736991-52-9
    • ~%
    • In-stock
      1-Boc-4-(2-Formylphenyl)piperazine|CS-W013995
      174855-57-3

    References

    • Richardson, Timothy I.; Ornstein, Paul L.; Briner, Karin; Fisher, Matthew J.; Backer, Ryan T.; Biggers, C. Kelly; Clay, Michael P.; Emmerson, Paul J.; Hertel, Larry W.; Hsiung, Hansen M.; Husain, Saba; Kahl, Steven D.; Lee, Jonathan A.; Lindstrom, Terry D.; Martinelli, Michael J.; Mayer, John P.; Mullaney, Jeffery T.; O'Brien, Thomas P.; Pawlak, Joseph M.; Revell, Kevin D.; Shah, Jikesh; Zgombick, John M.; Herr, R. Jason; Melekhov, Alex; Sampson, Peter B.; King, Chi-Hsin R. Journal of Medicinal Chemistry, 2004 , vol. 47, # 3 p. 744 - 755

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS06
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H301-H317
Precautionary Statements : P261-P264-P270-P272-P280-P302+P352-P330-P363-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   49.85
  • LogP   2.5562
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   2

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