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CS-W001157 4
Total: USD 88.00

6-Isoquinolinecarboxaldehyde

  • CAS No. 173089-81-1

  • Cat. No. CS-0021806
  • Purity≥97%
  • MDL No.MFCD06227438

*For research and further manufacturing use only, not for direct human use.

6-Isoquinolinecarboxaldehyde|CS-0021806

Structure of 173089-81-1

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General Information

  • CAS No. 173089-81-1
  • Cat. No. CS-0021806
  • Purity ≥97%
  • MDL No. MFCD06227438
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₇NO
  • Molecular Weight 157.17
  • Synonym(s) Isoquinoline-6-carbaldehyde
  • SMILES O=CC1=CC2=C(C=NC=C2)C=C1

Description

6-Isoquinolinecarboxaldehyde delivers a rigid, electron-deficient heteroaromatic scaffold ideal for coupling reactions. The aldehyde group enables direct functionalization in multistep syntheses, while the fused ring system provides structural stability and predictable regiochemistry under standard conditions.

Application

6-Isoquinolinecarboxaldehyde serves as a versatile building block in synthetic organic chemistry, enabling direct functionalization at the isoquinoline core. Its aldehyde functionality facilitates nucleophilic additions, reductive aminations, and condensation reactions under standard conditions. The molecule exhibits good bench stability and compatibility with common protecting groups, making it suitable for multi-step synthesis of heterocyclic scaffolds and potential intermediates in medicinal chemistry campaigns requiring nitrogen-containing aromatic systems.

Synthesis

  • Route1
    • In-stock
      6-Bromoisoquinoline|CS-D0847
      34784-05-9
    • null|null
      201230-82-2
    • ~40%
    • In-stock
      6-Isoquinolinecarboxaldehyde|CS-0021806
      173089-81-1

    References

    • US2003/199511 A1, ; Page/Page column 68 ;
  • Route2
    • null|null
      1105709-94-1
    • ~92%
    • In-stock
      6-Isoquinolinecarboxaldehyde|CS-0021806
      173089-81-1

    References

    • WO2009/11880 A2, ; Page/Page column 100-101 ; WO 2009/011880 A2

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   29.96
  • LogP   2.0473
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   1

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