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CS-W001157 4
Total: USD 88.00

Isoquinoline-7-carbaldehyde

  • CAS No. 87087-20-5

  • Cat. No. CS-0006109
  • Purity≥98%
  • MDL No.MFCD06227439

*For research and further manufacturing use only, not for direct human use.

Isoquinoline-7-carbaldehyde|CS-0006109

Structure of 87087-20-5

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General Information

  • CAS No. 87087-20-5
  • Cat. No. CS-0006109
  • Purity ≥98%
  • MDL No. MFCD06227439
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₇NO
  • Molecular Weight 157.17
  • Synonym(s) None
  • SMILES O=CC1=CC2=CN=CC=C2C=C1

Description

Isoquinoline-7-carbaldehyde delivers a rigid, electron-deficient heteroaromatic scaffold ideal for coupling reactions in medicinal chemistry. The aldehyde functionality enables direct integration into complex architectures via reductive amination or Grignard addition, while the para-positioned carbonyl enhances reactivity in transition-metal-catalyzed transformations.

Application

Isoquinoline-7-carbaldehyde serves as a versatile building block in medicinal chemistry, enabling efficient access to biologically relevant heterocyclic scaffolds. Its aldehyde functionality facilitates nucleophilic additions, reductive aminations, and condensation reactions under standard conditions. The molecule exhibits good bench stability and compatibility with common protecting groups, allowing straightforward incorporation into complex molecular architectures.

Synthesis

  • Route1
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      54004-38-5
    • ~%
    • In-stock
      Isoquinoline-7-carbaldehyde|CS-0006109
      87087-20-5

    References

    • Zhurnal Obshchei Khimii, , vol. 27, p. 734,739; engl. Ausg. S. 809, 813
  • Route2
    • null|null
      99060-14-7
    • ~%
    • In-stock
      Isoquinoline-7-carbaldehyde|CS-0006109
      87087-20-5

    References

    • Zhurnal Obshchei Khimii, , vol. 27, p. 734,739; engl. Ausg. S. 809, 813
  • Route3
    • null|null
      102014-89-1
    • ~%
    • In-stock
      Isoquinoline-7-carbaldehyde|CS-0006109
      87087-20-5

    References

    • Zhurnal Obshchei Khimii, , vol. 27, p. 734,739; engl. Ausg. S. 809, 813

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H312-H315-H319-H332-H335
Precautionary Statements : P260-P261-P264-P270-P271-P280-P301+P310-P302+P352-P304+P340-P304+P341-P305+P351+P338-P312-P330-P332+P313-P337+P313-P362+P364-P363-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   29.96
  • LogP   2.0473
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   1

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