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CS-W001157 4
Total: USD 88.00

4-(Methoxycarbonyl)thiophene-2-carboxylic acid

  • CAS No. 135080-15-8

  • Cat. No. CS-0542007
  • Molecule weight186.19
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

4-(Methoxycarbonyl)thiophene-2-carboxylic acid|CS-0542007

Structure of 135080-15-8

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General Information

  • CAS No. 135080-15-8
  • Cat. No. CS-0542007
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₆O₄S
  • Molecular Weight 186.19
  • Synonym(s) None
  • SMILES O=C(C1=CC(C(OC)=O)=CS1)O

Description

4-(Methoxycarbonyl)thiophene-2-carboxylic acid integrates a thiophene core with strategically positioned ester and carboxylic acid functionalities, enabling direct participation in coupling reactions. This bifunctional scaffold supports efficient derivatization for conjugated materials and bioactive molecule synthesis under standard conditions.

Application

4-(Methoxycarbonyl)thiophene-2-carboxylic acid serves as a versatile building block in heterocyclic synthesis, enabling efficient access to substituted thiophene scaffolds. Its dual functionality—carboxylic acid and ester groups—facilitates diverse transformations including amidation, coupling reactions, and cyclization processes. The molecule exhibits good bench stability and is compatible with standard purification methods, making it well-suited for use in medicinal chemistry and materials science applications.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   63.6
  • LogP   1.2329
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   2

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