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N-(2-Amino-4,6-dichloropyrimidine-5-yl)formamide Abacavir Impurity

  • CAS No. 171887-03-9

  • Cat. No. CS-0229546
  • Purity≥98%
  • MDL No.MFCD04112936

*For research and further manufacturing use only, not for direct human use.

N-(2-Amino-4,6-dichloropyrimidine-5-yl)formamide Abacavir Impurity|CS-0229546

Structure of 171887-03-9

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General Information

  • CAS No. 171887-03-9
  • Cat. No. CS-0229546
  • Purity ≥98%
  • MDL No. MFCD04112936
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₄Cl₂N₄O
  • Molecular Weight 207.02
  • Synonym(s) N-(2-Amino-4,6-dichloropyrimidin-5-yl)formamide
  • SMILES NC1=NC(=C(C(=N1)Cl)NC=O)Cl

Synthesis

  • Route1

    References

    • Lonza AG Patent: EP1188750 A1, 2002 ; Location in patent: Page 5 ;
  • Route2
    • 2,5-Diamino-4,6-dihydroxypyrimidine hydrochloride|CS-0008326
      56830-58-1
    • ~%
    • N-(2-Amino-4,6-dichloropyrimidine-5-yl)formamide Abacavir Impurity|CS-0229546
      171887-03-9

    References

    • US2007/265287 A1, ;
  • Route3

    References

    • US6271376 B1, ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   80.9
  • LogP   0.9339
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   2

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