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CS-W001157 4
Total: USD 88.00

TPEN

  • CAS No. 16858-02-9

  • Cat. No. CS-6042
  • Purity≥98%
  • MDL No.MFCD00036918

*For research and further manufacturing use only, not for direct human use.

TPEN|CS-6042

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General Information

  • CAS No. 16858-02-9
  • Cat. No. CS-6042
  • Purity ≥98%
  • MDL No. MFCD00036918
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₆H₂₈N₆
  • Molecular Weight None
  • Synonym(s) TPEDA
  • SMILES N(CC1=NC=CC=C1)(CC2=NC=CC=C2)CCN(CC3=NC=CC=C3)CC4=NC=CC=C4

Description

Chelating transition metals with exceptional affinity, N,N,N′,N′-Tetrakis(2-pyridylmethyl)ethylenediamine (CAS 16858-02-9) selectively sequesters Cu²⁺ and Zn²⁺ within cellular environments, disrupting redox-sensitive signaling cascades.

Application

N,N,N′,N′-Tetrakis(2-pyridylmethyl)ethylenediamine (CAS 16858-02-9) chelates labile zinc pools in apoptotic P19 cells to disrupt lentiviral Vpx trafficking and infection dynamics. This metal-binding capacity alters viral entry pathways. Researchers exploit this property in HEK293T and THP-1 models to probe Jembrana disease virus Vif function and host restriction mechanisms.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   58.04
  • LogP   3.9712
  • H_Acceptors   6
  • H_Donors   0
  • Rotatable_Bonds   11

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