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CS-W001157 4
Total: USD 88.00

(S)-tert-Butyl (2-amino-3-phenylpropyl)carbamate

  • CAS No. 167298-44-4

  • Cat. No. CS-0154450
  • Purity≥98%
  • MDL No.MFCD11858348

*For research and further manufacturing use only, not for direct human use.

(S)-tert-Butyl (2-amino-3-phenylpropyl)carbamate|CS-0154450

Structure of 167298-44-4

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General Information

  • CAS No. 167298-44-4
  • Cat. No. CS-0154450
  • Purity ≥98%
  • MDL No. MFCD11858348
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₄H₂₂N₂O₂
  • Molecular Weight 250.34
  • Synonym(s) tert-butyl N-[(2S)-2-amino-2-phenyl-ethyl]carbamate
  • SMILES CC(C)(OC(NC[C@@H](N)CC1=CC=CC=C1)=O)C

Description

(S)-tert-Butyl (2-amino-3-phenylpropyl)carbamate is a chiral building block featuring a stereodefined amino alcohol scaffold with a phenyl-substituted side chain. This bench-stable, moisture-tolerant reagent integrates seamlessly into peptide synthesis and asymmetric catalysis workflows. The protected amine facilitates selective functionalization while maintaining configurational integrity during downstream transformations.

Application

(S)-tert-Butyl (2-amino-3-phenylpropyl)carbamate serves as a valuable chiral building block for the synthesis of bioactive molecules, particularly in medicinal chemistry. Its robust tert-butyl carbamate (Boc) group enables facile protection and deprotection under mild acidic conditions, while the pendant primary amine facilitates diverse functionalization. The molecule exhibits excellent bench stability and compatibility with standard coupling reactions, making it ideal for peptide-like scaffold construction and asymmetric synthesis workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   64.35
  • LogP   2.0811
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   4

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