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CS-W001157 4
Total: USD 88.00

5-Formylnicotinic acid

  • CAS No. 893723-55-2

  • Cat. No. CS-0132499
  • Purity≥97%
  • MDL No.MFCD06254754
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

5-Formylnicotinic acid|CS-0132499

Structure of 893723-55-2

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Description

5-Formylnicotinic acid features a pyridine ring with strategically positioned formyl and carboxylic acid groups, enabling direct incorporation into bioconjugation workflows. The electron-deficient aromatic core supports efficient coupling reactions, while the formyl moiety offers a reactive handle for hydrazine- or amine-based derivatization under mild conditions.

Application

5-Formylnicotinic acid serves as a versatile building block in medicinal chemistry, enabling direct incorporation of both aldehyde and carboxylic acid functionalities into heterocyclic scaffolds. Its bench-stable nature and compatibility with standard coupling reactions facilitate efficient synthesis of bioactive molecules, including pyridine-based pharmaceutical intermediates and ligands for metal coordination. The aldehyde group permits selective transformations such as reductive amination or hydrazone formation, while the carboxylic acid supports amide and ester derivatization under routine conditions.

General Information

  • CAS No. 893723-55-2
  • Cat. No. CS-0132499
  • Purity ≥97%
  • MDL No. MFCD06254754
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₅NO₃
  • Molecular Weight 151.12
  • Synonym(s) None
  • SMILES O=C(C1=CC(C=O)=CN=C1)O

Computational Chemistry Data

  • TPSA   67.26
  • LogP   0.5923
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   2

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H312-H332
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P501

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