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CS-W001157 4
Total: USD 88.00

1-Boc-4-benzyl-4-piperidinecarboxylic acid

  • CAS No. 167263-11-8

  • Cat. No. CS-0040801
  • Purity≥98%
  • MDL No.MFCD02179131

*For research and further manufacturing use only, not for direct human use.

1-Boc-4-benzyl-4-piperidinecarboxylic acid|CS-0040801

Structure of 167263-11-8

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General Information

  • CAS No. 167263-11-8
  • Cat. No. CS-0040801
  • Purity ≥98%
  • MDL No. MFCD02179131
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₈H₂₅NO₄
  • Molecular Weight 319.40
  • Synonym(s) N-BOC-4-BENZYL-4-PIPERIDINECARBOXYLIC ACID
  • SMILES O=C(N1CCC(C(O)=O)(CC2=CC=CC=C2)CC1)OC(C)(C)C

Synthesis

  • Route1
    • null|null
      741687-06-9
    • ~86%
    • 1-Boc-4-benzyl-4-piperidinecarboxylic acid|CS-0040801
      167263-11-8

    References

    • ASTEX THERAPEUTICS LIMITED; THE INSTITUTE OF CANCER RESEARCH:ROYAL CANCER HOSPITAL; CANCER RESEARCH TECHNOLOGY LIMITED Patent: WO2007/125321 A2, 2007 ; Location in patent: Page/Page column 123 ; WO 2007/125321 A2
  • Route2

    References

    • D'Sidocky, Neil R.; Harris, Roy L.; Hegde, Sayee G.; Hilgraf, Robert; McCarrick, Margaret A.; McKie, Jeffrey A.; Mortensen, Deborah S.; Nadolny, Lisa; Perin-Ninkovic, Sophie M.; Sapienza, John J.; Wright, Jonathan L. Patent: US2008/242694 A1, 2008 ; Location in patent: Page/Page column 59 ; US 20080242694 A1
  • Route3
    • 1-(Tert-butyl) 4-ethyl 4-benzylpiperidine-1,4-dicarboxylate|CS-0336913
      167263-10-7
    • ~%
    • 1-Boc-4-benzyl-4-piperidinecarboxylic acid|CS-0040801
      167263-11-8

    References

    • Merck and Co., Inc. Patent: EP854870 B1, 2009 ; Location in patent: Page/Page column 27 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   66.84
  • LogP   3.331
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   3

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