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CS-W001157 4
Total: USD 88.00

1-Boc-3-benzyl-3-piperidinecarboxylic acid

  • CAS No. 170838-83-2

  • Cat. No. CS-M2147
  • Purity≥98%
  • MDL No.MFCD03840043

*For research and further manufacturing use only, not for direct human use.

1-Boc-3-benzyl-3-piperidinecarboxylic acid|CS-M2147

Structure of 170838-83-2

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General Information

  • CAS No. 170838-83-2
  • Cat. No. CS-M2147
  • Purity ≥98%
  • MDL No. MFCD03840043
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₈H₂₅NO₄
  • Molecular Weight 319.40
  • Synonym(s) None
  • SMILES CC(C)(C)OC(N1CCCC(C(O)=O)(CC2=CC=CC=C2)C1)=O

Description

1-Boc-3-benzyl-3-piperidinecarboxylic acid features a protected piperidine scaffold with a benzylated nitrogen and a Boc-regulated carboxylic acid, enabling direct incorporation into complex alkaloid frameworks. The sterically shielded tertiary amine and bench-stable Boc group streamline synthetic workflows in medicinal chemistry, supporting efficient coupling and cyclization sequences under standard conditions.

Application

1-Boc-3-benzyl-3-piperidinecarboxylic acid serves as a versatile building block for the synthesis of bioactive piperidine derivatives. The Boc group provides stable protection of the amine, enabling straightforward deprotection under mild acidic conditions. The benzyl substituent enhances solubility and facilitates downstream functionalization, while the carboxylic acid functionality supports efficient coupling reactions. This compound demonstrates excellent bench stability and compatibility with standard peptide and medicinal chemistry workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P260-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   66.84
  • LogP   3.331
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   3

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