Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

2-Iodo-1H-indole

  • CAS No. 26340-49-8

  • Cat. No. CS-0041513
  • Purity≥95%
  • MDL No.MFCD10699391

*For research and further manufacturing use only, not for direct human use.

2-Iodo-1H-indole|CS-0041513

Structure of 26340-49-8

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 26340-49-8
  • Cat. No. CS-0041513
  • Purity ≥95%
  • MDL No. MFCD10699391
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₆IN
  • Molecular Weight 243.04
  • Synonym(s) None
  • SMILES IC1=CC2=C(N1)C=CC=C2

Description

2-Iodo-1H-indole delivers a reactive iodine handle at the 2-position of the indole core, enabling efficient cross-coupling transformations. This bench-stable compound features a highly electrophilic carbon-iodine bond, facilitating palladium-catalyzed reactions with minimal decomposition. The electron-rich indole scaffold supports diverse functionalization pathways in medicinal chemistry and materials synthesis.

Application

2-Iodo-1H-indole serves as a versatile building block in C–H functionalization and transition-metal-catalyzed coupling reactions. The iodine atom enables reliable cross-coupling with palladium or nickel catalysts, facilitating the construction of biaryl and heteroaryl architectures. Its bench-stable nature and compatibility with diverse functional groups make it ideal for iterative synthesis in medicinal chemistry and materials science applications.

Synthesis

  • Route1
    • Indole, ≥99%|CS-1268948
      120-72-9
    • ~89%
    • In-stock
      2-Iodo-1H-indole|CS-0041513
      26340-49-8

    References

    • Merlic, Craig A.; You, Ying; McInnes, Daniel M.; Zechman, Andrea L.; Miller, Michael M.; Deng, Qiaolin Tetrahedron, 2001 , vol. 57, # 24 p. 5199 - 5212
  • Route2
    • 2-Iodo-1-(phenylsulfonyl)-1H-indole|CS-0733909
      99275-44-2
    • ~91%
    • In-stock
      2-Iodo-1H-indole|CS-0041513
      26340-49-8

    References

    • Kline Journal of Heterocyclic Chemistry, 1985 , vol. 22, # 2 p. 505 - 509
  • Route3

    References

    • Partridge, Benjamin M.; Hartwig, John F. Organic Letters, 2013 , vol. 15, # 1 p. 140 - 143

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05,GHS06
Signal Word : Danger
UN#: 2928
Class : 6.1(8)
Packing Group : Ⅱ
Hazard Statements : H302-H311-H315-H318
Precautionary Statements : P264-P270-P280-P302+P352-P330-P361+P364-P362+P364-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   15.79
  • LogP   2.7725
  • H_Acceptors   0
  • H_Donors   1
  • Rotatable_Bonds   0

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 2-Iodo-1H-indole sigma2-Iodo-1H-indole manufacturer2-Iodo-1H-indole price2-Iodo-1H-indole structure2-Iodo-1H-indole SDSbuy 2-Iodo-1H-indole2-Iodo-1H-indole supplier2-Iodo-1H-indole uses2-Iodo-1H-indole molecular weightprice of 2-Iodo-1H-indole2-Iodo-1H-indole chemical name formula of 2-Iodo-1H-indole
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label