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CS-W001157 4
Total: USD 88.00

(5-Bromo-2-methoxyphenyl)methanamine

  • CAS No. 166530-78-5

  • Cat. No. CS-W021112
  • Purity≥95%
  • MDL No.MFCD07786723

*For research and further manufacturing use only, not for direct human use.

(5-Bromo-2-methoxyphenyl)methanamine|CS-W021112

Structure of 166530-78-5

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General Information

  • CAS No. 166530-78-5
  • Cat. No. CS-W021112
  • Purity ≥95%
  • MDL No. MFCD07786723
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₀BrNO
  • Molecular Weight 216.08
  • Synonym(s) 5-BROMO-2-METHOXYBENZYLAMINE
  • SMILES NCC1=CC(Br)=CC=C1OC

Description

(5-Bromo-2-methoxyphenyl)methanamine features a brominated aromatic ring with ortho-methoxy and benzylic amine functionalities, enabling direct coupling in cross-coupling reactions. This bench-stable scaffold integrates readily into bioactive molecule synthesis, particularly for pharmaceutical intermediates requiring halogen-directed functionalization.

Application

(5-Bromo-2-methoxyphenyl)methanamine serves as a versatile building block for the synthesis of biologically active arylamines. Its bromo and methoxy substituents enable subsequent cross-coupling reactions and directed functionalization, while the primary amine facilitates conjugation or derivatization. The compound exhibits good bench stability and is compatible with standard purification protocols, making it well-suited for medicinal chemistry campaigns and API intermediate development.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   35.25
  • LogP   1.9164
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   2

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