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CS-W001157 4
Total: USD 88.00

[2-(1H-Pyrrol-1-yl)ethyl]amine

  • CAS No. 29709-35-1

  • Cat. No. CS-0072896
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

[2-(1H-Pyrrol-1-yl)ethyl]amine|CS-0072896

Structure of 29709-35-1

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General Information

  • CAS No. 29709-35-1
  • Cat. No. CS-0072896
  • Purity ≥95%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₀N₂
  • Molecular Weight 110.16
  • Synonym(s) 2-(1H-pyrrol-1-yl)ethanamine
  • SMILES NCCN1C=CC=C1

Application

[2-(1H-Pyrrol-1-yl)ethyl]amine serves as a versatile building block in medicinal chemistry, enabling the synthesis of pyrrole-containing bioactive molecules. Its primary amine functionality facilitates straightforward derivatization, while the pendant pyrrole ring offers π-conjugation and hydrogen-bonding capacity. The compound exhibits good bench stability and compatibility with standard coupling reactions, making it suitable for modular assembly of heterocyclic scaffolds in API development.

Synthesis

  • Route1
    • null|null
      109-97-7
    • 2-Chloroethanamine hydrochloride Ifosfamide  Impurity|CS-0229451
      870-24-6
    • ~84%
    • In-stock
      [2-(1H-Pyrrol-1-yl)ethyl]amine|CS-0072896
      29709-35-1

    References

    • He, Yuwei; Lin, Maohui; Li, Zhongmin; Liang, Xinting; Li, Guilong; Antilla, Jon C. Organic Letters, 2011 , vol. 13, # 17 p. 4490 - 4493
  • Route2
    • N-(2-(1H-pyrrol-1-yl)ethyl)acetamide|CS-0326492
      73627-16-4
    • ~66%
    • In-stock
      [2-(1H-Pyrrol-1-yl)ethyl]amine|CS-0072896
      29709-35-1

    References

    • Pleus, Susanne; Schwientek, Marion Synthetic Communications, 1997 , vol. 27, # 17 p. 2917 - 2930
  • Route3
    • null|null
      696-59-3
    • ~56%
    • In-stock
      [2-(1H-Pyrrol-1-yl)ethyl]amine|CS-0072896
      29709-35-1

    References

    • Syntex (U.S.A.) Inc. Patent: US5041442 A1, 1991 ; US 5041442 A

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05,GHS07
Signal Word : Danger
UN#: 1760
Class : 8
Packing Group : Ⅲ
Hazard Statements : H227-H315-H318-H335
Precautionary Statements : P210-P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P370+P378-P403-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   30.95
  • LogP   0.4468
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   2

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