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CS-W001157 4
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(4R,4'R)-2,2'-Methylenebis[4,5-dihydro-4-(phenylmethyl)oxazole]

  • CAS No. 1646862-39-6

  • Cat. No. CS-0113774
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(4R,4'R)-2,2'-Methylenebis[4,5-dihydro-4-(phenylmethyl)oxazole]|CS-0113774

Structure of 1646862-39-6

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General Information

  • CAS No. 1646862-39-6
  • Cat. No. CS-0113774
  • Purity ≥95%
  • MDL No. None
  • Storage -20°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₁H₂₂N₂O₂
  • Molecular Weight 334.41
  • Synonym(s) None
  • SMILES C1(CC2=N[C@H](CC3=CC=CC=C3)CO2)=N[C@H](CC4=CC=CC=C4)CO1

Description

This chiral bisoxazole scaffold features a rigid methylene-bridged architecture that enhances structural stability and stereochemical integrity. Designed for asymmetric synthesis, it integrates into catalytic systems where defined spatial orientation enables high enantioselectivity in bond-forming reactions under standard conditions.

Application

(4R,4'R)-2,2'-Methylenebis[4,5-dihydro-4-(phenylmethyl)oxazole] serves as a chiral bis-oxazole scaffold with defined stereochemistry at the 4 and 4' positions. It functions as a versatile building block in asymmetric synthesis, enabling the construction of complex heterocyclic systems through controlled coupling reactions. The methylene bridge provides rigidity and enhances structural integrity, while the benzylic substituents offer compatibility with standard functional group manipulations. Its bench-stable nature and predictable reactivity make it suitable for iterative synthetic strategies in medicinal chemistry and catalytic system development.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H320-H335
Precautionary Statements : P261-P280-P302+P352

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Computational Chemistry Data

  • TPSA   43.18
  • LogP   3.4565
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   6

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