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Structure of 1642298-59-6
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3-(Fluoromethyl)azetidine hydrochloride delivers a strained, electron-deficient azetidine core paired with a reactive fluoromethyl group. This combination enables direct functionalization in late-stage synthesis and facilitates selective C–H activation. The hydrochloride salt enhances solubility and stability under standard conditions, simplifying handling in medicinal chemistry workflows.
3-(Fluoromethyl)azetidine hydrochloride serves as a valuable building block for medicinal chemistry, enabling the introduction of a fluoromethyl group at the azetidine nitrogen. Its bench-stable hydrochloride salt facilitates handling and purification, while the fluoromethyl moiety offers enhanced metabolic stability and modulates electronic properties in target molecules. The compound participates reliably in nucleophilic substitution and reductive amination reactions, supporting efficient access to diverse heterocyclic scaffolds relevant to drug discovery.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319
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Precautionary Statements : P264-P280-P302+P352-P362
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Lot numbers can be found on the outside label of a product: