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Structure of 164161-49-3
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Methyl 5-benzyloxy-4-methoxy-2-nitrobenzoate features a nitro-substituted aromatic core with orthogonal protecting groups: a benzyloxy moiety at C5 and a methoxy group at C4. This combination enables selective deprotection sequences in complex synthesis, particularly in pharmaceutical intermediates where orthogonal functionalization is required. The molecule exhibits enhanced stability under standard bench conditions and facilitates efficient coupling reactions in late-stage derivatization workflows.
Methyl 5-benzyloxy-4-methoxy-2-nitrobenzoate serves as a versatile building block in synthetic organic chemistry, enabling efficient access to substituted aromatic scaffolds. The nitro group facilitates subsequent reduction and functionalization, while the benzyloxy and methoxy groups offer orthogonal protection strategies. Its stability under standard reaction conditions and compatibility with common coupling and deprotection protocols make it well-suited for iterative synthesis workflows in medicinal chemistry and process development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: