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2,5-Diazaspiro[3.4]octan-6-one hydrochloride

  • CAS No. 1630906-86-3

  • Cat. No. CS-0052145
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

2,5-Diazaspiro[3.4]octan-6-one hydrochloride|CS-0052145

Structure of 1630906-86-3

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General Information

  • CAS No. 1630906-86-3
  • Cat. No. CS-0052145
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₁ClN₂O
  • Molecular Weight 162.62
  • Synonym(s) 2,5-DIAZASPIRO[3.4]OCTAN-6-ONE HCL
  • SMILES Cl.O=C1CCC2(CNC2)N1

Description

2,5-Diazaspiro[3.4]octan-6-one hydrochloride delivers a rigid, bicyclic scaffold with dual nitrogen atoms positioned for strategic incorporation into bioactive molecules. This bench-stable, moisture-tolerant core enables efficient access to constrained heterocyclic architectures in medicinal chemistry and chemical biology applications.

Application

2,5-Diazaspiro[3.4]octan-6-one hydrochloride serves as a stable, crystalline scaffold for the synthesis of bioactive heterocycles, enabling efficient access to spirocyclic amine derivatives via standard reductive amination and coupling protocols. Its functionalized core exhibits excellent compatibility with diverse reaction conditions, facilitating modular derivatization for medicinal chemistry applications. The hydrochloride salt enhances solubility and handling in aqueous or protic media, supporting robust performance in multi-step syntheses.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   41.13
  • LogP   -0.3398
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   0

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