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CS-W001157 4
Total: USD 88.00

N-(3-Aminophenyl)acrylamide

  • CAS No. 16230-24-3

  • Cat. No. CS-0048855
  • Molecule weight162.19
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

N-(3-Aminophenyl)acrylamide|CS-0048855

Structure of 16230-24-3

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General Information

  • CAS No. 16230-24-3
  • Cat. No. CS-0048855
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₀N₂O
  • Molecular Weight 162.19
  • Synonym(s) N-(3-aminophenyl)prop-2-enamide
  • SMILES NC1=CC(NC(=O)C=C)=CC=C1

Description

N-(3-Aminophenyl)acrylamide features a conjugated acrylamide warhead linked to a meta-aminophenyl group, enabling targeted covalent modification in chemical biology applications. This electron-rich scaffold facilitates efficient Michael additions and integrates readily into probe design for protein labeling.

Application

N-(3-Aminophenyl)acrylamide serves as a versatile building block for medicinal chemistry and materials science, enabling efficient access to conjugated systems via its amide and vinyl functionalities. The ortho-aminoaryl group facilitates directed metalation and downstream functionalization, while the acrylamide moiety supports Michael addition reactions and polymerization applications. Bench-stable and readily purified by recrystallization, it functions effectively in multi-step syntheses requiring moderate functional group tolerance and predictable reactivity.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   55.12
  • LogP   1.3933
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   2

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