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CS-W001157 4
Total: USD 88.00

N-(3-Aminophenyl)acetamide

  • CAS No. 102-28-3

  • Cat. No. CS-W019904
  • Purity≥98%
  • MDL No.MFCD00025229

*For research and further manufacturing use only, not for direct human use.

N-(3-Aminophenyl)acetamide|CS-W019904

Structure of 102-28-3

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General Information

  • CAS No. 102-28-3
  • Cat. No. CS-W019904
  • Purity ≥98%
  • MDL No. MFCD00025229
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₀N₂O
  • Molecular Weight 150.18
  • Synonym(s) 3-Amino-N-acetylaniline; 3'-Aminoacetanilide; N-Acetyl-1,3-diaminobenzene; N-Acetyl-m-phenylenediamine; NSC 165576; m-(Acetylamino)aniline; m-Acetamidoaniline; m-Aminoacetanilide; N-Acetyl-m-fenylendiamin [Czech]
  • SMILES CC(NC1=CC=CC(N)=C1)=O

Description

N-(3-Aminophenyl)acetamide features a primary amine directly conjugated to an aromatic ring, enabling direct functionalization in pharmaceutical and agrochemical synthesis. The acetamide group provides enhanced solubility and stability under standard conditions, facilitating integration into complex molecular architectures via amidation or coupling reactions.

Synthesis

  • Route1
    • (Z)-1-(3-aminophenyl)ethan-1-one oxime|CS-0573341
      6011-18-3
    • ~96%
    • In-stock
      N-(3-Aminophenyl)acetamide|CS-W019904
      102-28-3

    References

    • Li, Dongmei; Shi, Feng; Guo, Shu; Deng, Youquan Tetrahedron Letters, 2005 , vol. 46, # 4 p. 671 - 674
  • Route2
    • N-(3-Chlorophenyl)acetamide|CS-0277313
      588-07-8
    • ~46%
    • In-stock
      N-(3-Aminophenyl)acetamide|CS-W019904
      102-28-3

    References

    • Cheung, Chi Wai; Surry, David S.; Buchwald, Stephen L. Organic Letters, 2013 , vol. 15, # 14 p. 3734 - 3737
  • Route3

    References

    • Boyle, Elaine M.; McCabe, Thomas; Gunnlaugsson, Thorfinnur Supramolecular Chemistry, 2010 , vol. 22, # 10 p. 586 - 597

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   55.12
  • LogP   1.2272
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

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