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CS-W001157 4
Total: USD 88.00

3-Bromo-4-iodo-1-methyl-1H-pyrazole

  • CAS No. 1619993-43-9

  • Cat. No. CS-0438077
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

3-Bromo-4-iodo-1-methyl-1H-pyrazole|CS-0438077

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General Information

  • CAS No. 1619993-43-9
  • Cat. No. CS-0438077
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₄BrIN₂
  • Molecular Weight 286.90
  • Synonym(s) None
  • SMILES CN1N=C(Br)C(I)=C1

Description

3-Bromo-4-iodo-1-methyl-1H-pyrazole is a halogenated pyrazole derivative featuring complementary reactive sites for cross-coupling applications. The bromo and iodo substituents enable sequential functionalization, while the methyl group enhances solubility and electronic modulation. This compound serves as a robust scaffold in synthetic methodology development.

Application

3-Bromo-4-iodo-1-methyl-1H-pyrazole serves as a versatile dihalogenated pyrazole building block for transition-metal-catalyzed cross-coupling reactions. The bromo and iodo substituents enable sequential functionalization via palladium- or nickel-mediated coupling, facilitating the assembly of complex heterocyclic architectures. Its bench-stable crystalline form and orthogonal reactivity profile support efficient synthesis of diversified pyrazole-based scaffolds in medicinal chemistry and agrochemical research.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   17.82
  • LogP   1.7872
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   0

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