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CS-W001157 4
Total: USD 88.00

3,5-Dibromo-1-methyl-1H-pyrazole

  • CAS No. 1361019-05-7

  • Cat. No. CS-0097502
  • Purity≥97%
  • MDL No.MFCD28399417

*For research and further manufacturing use only, not for direct human use.

3,5-Dibromo-1-methyl-1H-pyrazole|CS-0097502

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General Information

  • CAS No. 1361019-05-7
  • Cat. No. CS-0097502
  • Purity ≥97%
  • MDL No. MFCD28399417
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₄Br₂N₂
  • Molecular Weight 239.90
  • Synonym(s) 1H-Pyrazole, 3,5-dibromo-1-methyl-
  • SMILES CN1N=C(Br)C=C1Br

Description

3,5-Dibromo-1-methyl-1H-pyrazole features two bromine substituents at the 3 and 5 positions of the pyrazole ring, enhancing electrophilic reactivity. The methyl group at N1 provides steric and electronic modulation, improving stability under standard handling conditions. This bench-stable heterocycle serves as a key building block in medicinal chemistry and materials science, enabling direct coupling reactions without pre-functionalization.

Application

3,5-Dibromo-1-methyl-1H-pyrazole serves as a versatile building block for the synthesis of brominated heterocyclic scaffolds. Its regioselective substitution pattern enables efficient functionalization in cross-coupling and electrophilic aromatic substitution reactions. The methyl group enhances stability and facilitates purification, while the bromine atoms provide orthogonal handles for sequential derivatization. This compound is particularly valuable in medicinal chemistry for constructing diverse pyrazole-based pharmacophores.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

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Computational Chemistry Data

  • TPSA   17.82
  • LogP   1.9451
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   0

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