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Structure of 161043-38-5
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1-(Bromomethyl)bicyclo[1.1.1]pentane features a highly strained, rigid cage structure that imparts exceptional stability and reactivity control. The bromomethyl group enables efficient functionalization in cross-coupling and bioconjugation workflows, while the bicyclic framework resists decomposition under standard conditions. This compound serves as a robust scaffold for probe development and medicinal chemistry applications.
1-(Bromomethyl)bicyclo[1.1.1]pentane serves as a versatile, sterically constrained alkylating agent enabling efficient introduction of the bicyclo[1.1.1]pentane scaffold into diverse molecular architectures. Its primary bromide functionality facilitates nucleophilic substitution under mild conditions, offering high functional group tolerance and excellent bench stability. The rigid, compact structure enhances metabolic stability and modulates physicochemical properties in medicinal chemistry applications, making it a practical building block for targeted synthesis of bioactive compounds and advanced intermediates.
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GHS Pictogram :
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GHS No : GHS02,GHS05
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Signal Word : Danger
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UN#: 2920
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Class : 8,3
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Packing Group : Ⅱ
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Hazard Statements : H225-H314
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Precautionary Statements : P210-P233-P240-P241-P242-P243-P260-P264-P280-P301+P330+P331-P304+P340-P363-P370+P378-P405-P501
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Lot numbers can be found on the outside label of a product: