MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH

Name: MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH
Brand: ChemScene
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CAS No. 1599440-25-1
Cat. No. CS-0145893
Purity≥98%
MDL No.None

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH|CS-0145893

Structure of 1599440-25-1

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General Information

CAS No. 1599440-25-1
Cat. No. CS-0145893
Purity ≥98%
MDL No. None
Storage 4°C, sealed storage, away from moisture
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₂₈H₃₆N₆O₁₀
Molecular Weight 616.62
Synonym(s) (S)-10-Benzyl-23-(2,5-Dioxo-2,5-Dihydro-1H-Pyrrol-1-Yl)-6,9,12,15,18-Pentaoxo-3-Oxa-5,8,11,14,17-Pentaazatricosan-1-Oic Acid
SMILES OC(COCNC(CNC([C@@H](NC(CNC(CNC(CCCCCN1C(C=CC1=O)=O)=O)=O)=O)CC2=CC=CC=C2)=O)=O)=O

Description

MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH features a hydrophilic polyethylene glycol linker flanked by a tetrapeptide sequence, enabling efficient conjugation in bioactive molecule synthesis. This design supports stable, water-soluble derivatization under physiological conditions, ideal for peptide-based probe development and targeted delivery systems.

Application

MC-Gly-Gly-Phe-Gly-NH-CH₂-O-CH₂COOH serves as a stable, bifunctional peptide scaffold enabling site-specific conjugation in bioconjugation workflows. The N-terminal amine and C-terminal carboxylic acid facilitate efficient coupling reactions, while the glycosylated linker enhances solubility and metabolic stability. This sequence supports modular synthesis of peptide-drug conjugates and protein labeling reagents with predictable reactivity and ease of purification.

Safety Information

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GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319
Precautionary Statements : P264-P270-P280-P302+P352-P330-P362+P364-P501

Quality Control

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Computational Chemistry Data

TPSA 229.41
LogP -2.2772
H_Acceptors 9
H_Donors 6
Rotatable_Bonds 20

Other Classifications

Life Science Linker Cleavable Linkers

Life Science Linker Maleimide Linkers

Life Science ADC Related Compound ADC Linker

Chemical Biology Pharmaceutical Development and Drug Discovery Research Reagents Antibody-Drug Conjugates (ADC) Preparation Research Reagents Cross-Linkers

Chemical Biology PEGylation PEG Oligomers

Biochemistry Biochemicals and Reagents Antibody-Drug Conjugates (ADC) Preparation Research Reagents Cross-Linkers

Biochemistry Biochemicals and Reagents Bioconjugation PEGylation Reagents and PEG Spacers

Biochemistry Pharmaceutical Development and Drug Discovery Research Antibody-Drug Conjugates (ADC) Preparation Research Reagents Cross-Linkers

Key Words

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MC-Gly-Gly-Phe-Gly-NH-CH2-O-CH2COOH

CAS No. 1599440-25-1

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