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Structure of 1590409-73-6
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8-Bromopyrido[3,4-b]pyrazin-5(6H)-one is a brominated heterocyclic scaffold featuring a fused pyridopyrazine core with a ketone at the 5-position. This electron-deficient system enables direct functionalization in cross-coupling reactions and serves as a key intermediate in the synthesis of bioactive nitrogen-rich compounds. The bromine atom provides a high-affinity handle for palladium-catalyzed transformations, while the planar structure supports π-stacking interactions in medicinal chemistry applications.
8-Bromopyrido[3,4-b]pyrazin-5(6H)-one serves as a versatile heterocyclic building block for medicinal chemistry and process development. Its bromine substituent enables palladium-catalyzed cross-coupling reactions, facilitating the construction of biaryl and aryl-substituted scaffolds. The pyrido[3,4-b]pyrazinone core offers enhanced metabolic stability and hydrogen-bonding capacity, making it suitable for targeted drug discovery programs. The compound exhibits good bench stability and is amenable to standard purification methods.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: