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CS-W001157 4
Total: USD 88.00

1-(6-Bromonaphthalen-2-yl)ethanone

  • CAS No. 1590-25-6

  • Cat. No. CS-0041458
  • Purity≥98%
  • MDL No.MFCD00126480

*For research and further manufacturing use only, not for direct human use.

1-(6-Bromonaphthalen-2-yl)ethanone|CS-0041458

Structure of 1590-25-6

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General Information

  • CAS No. 1590-25-6
  • Cat. No. CS-0041458
  • Purity ≥98%
  • MDL No. MFCD00126480
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₉BrO
  • Molecular Weight None
  • Synonym(s) Ethanone, 1-(6-bromo-2-naphthalenyl)-
  • SMILES CC(C1=CC=C2C=C(Br)C=CC2=C1)=O

Description

1-(6-Bromonaphthalen-2-yl)ethanone features a brominated naphthalene core paired with a ketone-functionalized ethyl side chain, enabling direct integration into cross-coupling and electrophilic substitution reactions. This bench-stable reagent delivers high regiochemical fidelity in C–C bond formation under standard conditions.

Application

1-(6-Bromonaphthalen-2-yl)ethanone serves as a versatile building block for transition-metal-catalyzed cross-coupling reactions, enabling efficient construction of biaryl scaffolds under standard Suzuki-Miyaura and Stille conditions. The bromine substituent exhibits high reactivity and functional group tolerance, while the ketone moiety provides a handle for further derivatization via nucleophilic addition or enolization. Its bench-stable solid form facilitates handling and purification in synthetic workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: 3077
Class : 9
Packing Group : Ⅲ
Hazard Statements : H319-H401
Precautionary Statements : P264-P273-P280-P305+P351+P338-P337+P313-P501

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Computational Chemistry Data

  • TPSA   17.07
  • LogP   3.8049
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   1

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