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Structure of 158580-93-9
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3-Chloro-4-(trifluoromethoxy)benzoic acid features a trifluoromethoxy group that imparts enhanced electron-withdrawal and metabolic stability, while the chloro substituent provides a site for downstream functionalization. This aromatic carboxylic acid serves as a key building block in pharmaceutical synthesis, offering robustness under standard reaction conditions and compatibility with diverse coupling chemistries.
3-Chloro-4-(trifluoromethoxy)benzoic acid serves as a versatile building block in medicinal chemistry, enabling the synthesis of bioactive heterocycles and pharmaceutical intermediates. Its ortho-chloro and para-trifluoromethoxy groups provide enhanced metabolic stability and modulated lipophilicity. The carboxylic acid functionality facilitates direct coupling reactions and salt formation, supporting efficient purification and downstream derivatization in multi-step syntheses.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: