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Structure of 83279-39-4
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3-Chloro-4-(trifluoromethoxy)benzaldehyde features a trifluoromethoxy group that enhances electron-withdrawal and metabolic stability, while the chloro substituent directs electrophilic substitution. This combination enables efficient coupling in Suzuki-Miyaura and Ullmann reactions, delivering complex heterocycles with high functional group tolerance under standard conditions.
3-Chloro-4-(trifluoromethoxy)benzaldehyde serves as a valuable building block in medicinal chemistry and agrochemical synthesis, enabling efficient access to diverse heterocyclic scaffolds. Its electron-withdrawing trifluoromethoxy group enhances electrophilicity at the carbonyl center, facilitating nucleophilic additions and condensation reactions. The chloro substituent provides a handle for further functionalization via cross-coupling or substitution. Bench-stable and readily purified by recrystallization, it functions reliably in standard synthetic workflows requiring high chemical fidelity.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: