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CS-W001157 4
Total: USD 88.00

2-Oxo-1,2-dihydroquinoline-4-carboxylic acid

  • CAS No. 15733-89-8

  • Cat. No. CS-W015953
  • Purity≥98%
  • MDL No.MFCD00464512

*For research and further manufacturing use only, not for direct human use.

2-Oxo-1,2-dihydroquinoline-4-carboxylic acid|CS-W015953

Structure of 15733-89-8

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General Information

  • CAS No. 15733-89-8
  • Cat. No. CS-W015953
  • Purity ≥98%
  • MDL No. MFCD00464512
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₇NO₃
  • Molecular Weight 189.17
  • Synonym(s) 2-Hydroxyquinoline-4-carboxylic acid
  • SMILES O=C(C1=CC(NC2=C1C=CC=C2)=O)O

Description

A modified lysine derivative for the preparation of chromogenically-labeled peptides by Fmoc SPPS.The Dnp group is the preferred quencher for use in conjunction with the Mca fluorophore, making it an extremely useful tool for the synthesis of fluorescence-quenched peptide substrates. Associated Protocols and Technical ArticlesCleavage and Deprotection Protocols for Fmoc SPPSChromogenic Labeling of Synthetic Peptides

Synthesis

  • Route1
    • null|null
      141-82-2
    • In-stock
      Isatin|CS-W020128
      91-56-5
    • ~66%
    • In-stock
      2-Oxo-1,2-dihydroquinoline-4-carboxylic acid|CS-W015953
      15733-89-8

    References

    • El Ashry, El Sayed H.; Ramadan, El Sayed; Hamid, Hamida Abdel; Hagar, Mohamed Synthetic Communications, 2005 , vol. 35, # 17 p. 2243 - 2250
  • Route2

    References

    • El Ashry, El Sayed H.; Ramadan, El Sayed; Hamid, Hamida Abdel; Hagar, Mohamed Synthetic Communications, 2005 , vol. 35, # 17 p. 2243 - 2250
  • Route3
    • In-stock
      2-Chloroquinoline-4-carboxylic acid|CS-W015258
      5467-57-2
    • ~%
    • 2-Imino-1,2-dihydroquinoline-4-carboxylic acid|CS-0270246
      157915-68-9
    • In-stock
      2-Oxo-1,2-dihydroquinoline-4-carboxylic acid|CS-W015953
      15733-89-8

    References

    • Journal of the American Chemical Society, , vol. 68, p. 2714,2716

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P260-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   70.16
  • LogP   1.2263
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

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