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2-Oxo-1,2-dihydroquinoline-7-carboxylic acid

  • CAS No. 320349-89-1

  • Cat. No. CS-0188292
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

2-Oxo-1,2-dihydroquinoline-7-carboxylic acid|CS-0188292

Structure of 320349-89-1

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General Information

  • CAS No. 320349-89-1
  • Cat. No. CS-0188292
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₇NO₃
  • Molecular Weight 189.17
  • Synonym(s) 2-hydroxyquinoline-7-carboxylic acid
  • SMILES O=C(O)C=1C=CC=2C=CC(=O)NC2C1

Description

This quinoline-based carboxylic acid features a ketone at the 2-position and a carboxyl group at the 7-position, creating a rigid, electron-deficient scaffold. The conjugated system enables direct integration into heterocyclic synthesis, while the acidic functionality supports salt formation and derivatization under standard conditions.

Application

2-Oxo-1,2-dihydroquinoline-7-carboxylic acid serves as a versatile scaffold for heterocyclic synthesis, enabling efficient access to quinoline-based pharmacophores. Its carboxylic acid functionality facilitates direct derivatization and conjugation, while the enone system supports Michael addition and cycloaddition reactions. Bench-stable and compatible with standard purification methods, it functions effectively in multi-step synthetic sequences targeting bioactive molecules.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   70.16
  • LogP   1.2263
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

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