Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

5-Bromo-4-pyrimidinecarboxylic acid

  • CAS No. 64224-60-8

  • Cat. No. CS-W008913
  • Purity≥95%
  • MDL No.MFCD09754104

*For research and further manufacturing use only, not for direct human use.

5-Bromo-4-pyrimidinecarboxylic acid|CS-W008913

Structure of 64224-60-8

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 64224-60-8
  • Cat. No. CS-W008913
  • Purity ≥95%
  • MDL No. MFCD09754104
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₃BrN₂O₂
  • Molecular Weight None
  • Synonym(s) 5-Bromopyrimidine-4-carboxylic acid; 5-Bromo-4-pyrimidinecarboxylicacid
  • SMILES O=C(C1=NC=NC=C1Br)O

Description

5-Bromo-4-pyrimidinecarboxylic acid features a bromine substituent at the 5-position and a carboxylic acid group at the 4-position of the pyrimidine ring, providing a versatile scaffold for synthetic modifications. This electron-deficient heterocycle enables efficient coupling reactions in medicinal chemistry and materials science applications.

Application

5-Bromo-4-pyrimidinecarboxylic acid serves as a versatile building block for the synthesis of heterocyclic scaffolds and pharmaceutical intermediates. Its bromo group enables palladium-catalyzed cross-coupling reactions, while the carboxylic acid facilitates derivatization via amide formation or esterification. The compound exhibits good bench stability and is compatible with standard purification techniques, making it well-suited for use in medicinal chemistry campaigns and process development workflows.

Synthesis

  • Route1
    • null|null
      21577-50-4
    • null|null
      463-52-5
    • ~52%
    • In-stock
      5-Bromo-4-pyrimidinecarboxylic acid|CS-W008913
      64224-60-8

    References

    • Duan, Hongliang; Ning, Mengmeng; Chen, Xiaoyan; Zou, Qingan; Zhang, Liming; Feng, Ying; Zhang, Lina; Leng, Ying; Shen, Jianhua Journal of Medicinal Chemistry, 2012 , vol. 55, # 23 p. 10475 - 10489

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   63.08
  • LogP   0.9373
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 5-Bromo-4-pyrimidinecarboxylic acid sigma5-Bromo-4-pyrimidinecarboxylic acid manufacturer5-Bromo-4-pyrimidinecarboxylic acid price5-Bromo-4-pyrimidinecarboxylic acid structure5-Bromo-4-pyrimidinecarboxylic acid SDSbuy 5-Bromo-4-pyrimidinecarboxylic acid5-Bromo-4-pyrimidinecarboxylic acid supplier5-Bromo-4-pyrimidinecarboxylic acid uses5-Bromo-4-pyrimidinecarboxylic acid molecular weightprice of 5-Bromo-4-pyrimidinecarboxylic acid5-Bromo-4-pyrimidinecarboxylic acid chemical name formula of 5-Bromo-4-pyrimidinecarboxylic acid
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label