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CS-W001157 4
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7-Fluorobenzo[d]thiazole-2(3H)-thione

  • CAS No. 154327-29-4

  • Cat. No. CS-0134610
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

7-Fluorobenzo[d]thiazole-2(3H)-thione|CS-0134610

Structure of 154327-29-4

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General Information

  • CAS No. 154327-29-4
  • Cat. No. CS-0134610
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₄FNS₂
  • Molecular Weight 185.24
  • Synonym(s) 7-Fluoro-3H-benzothiazole-2-thione
  • SMILES S=C1SC2=C(F)C=CC=C2N1

Description

7-Fluorobenzo[d]thiazole-2(3H)-thione delivers a fluorinated heterocyclic scaffold with enhanced electron-withdrawing character, enabling efficient coupling in cross-coupling and metal-ligand coordination reactions. The thione functionality provides a robust anchor for transition metals while maintaining stability under standard bench conditions.

Application

7-Fluorobenzo[d]thiazole-2(3H)-thione serves as a versatile heterocyclic building block in medicinal chemistry, enabling efficient access to thiazole-based scaffolds. Its fluorinated aromatic core enhances metabolic stability and modulates electronic properties, while the thione functionality facilitates metal coordination and participation in nucleophilic substitution reactions. The compound exhibits bench-stable handling and compatibility with standard synthetic transformations, supporting its use in the development of bioactive molecules and functional materials.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   15.79
  • LogP   3.09799
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

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